3eym

X-ray diffraction
2.8Å resolution

Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-137030 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin HA1 chain Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 321 amino acids
Theoretical weight: 35.37 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03437 (Residues: 25-345; Coverage: 58%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin HA2 chain Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 172 amino acids
Theoretical weight: 19.91 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03437 (Residues: 346-517; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41
Unit cell:
a: 160.465Å b: 160.464Å c: 176.548Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.217