3eyf

X-ray diffraction
2.3Å resolution

Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide

Released:
Entry authors: Thomson CA, Bryson S, McLean GR, Creagh AL, Pai EF, Schrader JW

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
IGK@ protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 216 amino acids
Theoretical weight: 23.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PJF2 (Residues: 21-114, 115-235; Coverage: 100%)
Gene name: IGK@
Sequence domains:
Structure domains: Immunoglobulins
IgG heavy chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 242 amino acids
Theoretical weight: 25.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q68CN4 (Residues: 20-247; Coverage: 51%)
Gene name: DKFZp686E23209
Sequence domains:
Structure domains: Immunoglobulins
Envelope glycoprotein B Chains: E, F
Molecule details ›
Chains: E, F
Length: 11 amino acids
Theoretical weight: 1.24 KDa
Source organism: Human herpesvirus 5 strain Towne
Expression system: Not provided
UniProt:
  • Canonical: P13201 (Residues: 69-78; Coverage: 1%)
Gene names: UL55, gB

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 63.3Å b: 103.5Å c: 152.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.23
Expression systems:
  • Escherichia coli
  • Not provided