3ews

X-ray diffraction
2.7Å resolution

Human DEAD-box RNA-helicase DDX19 in complex with ADP

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent RNA helicase DDX19B Chains: A, B
Molecule details ›
Chains: A, B
Length: 445 amino acids
Theoretical weight: 50.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UMR2 (Residues: 54-475; Coverage: 88%)
Gene names: DBP5, DDX19, DDX19B, TDBP
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21
Unit cell:
a: 81.58Å b: 47.61Å c: 124.69Å
α: 90° β: 95.4° γ: 90°
R-values:
R R work R free
0.192 0.188 0.26
Expression system: Escherichia coli