› 3euw

X-ray diffraction
2.3Å resolution

Crystal Structure of a Myo-inositol dehydrogenase from Corynebacterium glutamicum ATCC 13032

Released:
DOI: 10.2210/pdb3euw/pdb
PDB entry 3euw coloured by chain, front view.
PDB entry 3euw coloured by chain, side view.
PDB entry 3euw coloured by chain, top view.
Source organism: Corynebacterium glutamicum ATCC 13032
Entry authors: Kumaran D, Mahmood A, Burley SK, Swaminathan S, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
Myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185589 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Predicted dehydrogenases and related proteins Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 344 amino acids
Theoretical weight: 37.66 KDa
Source organism: Corynebacterium glutamicum ATCC 13032
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NL86 (Residues: 2-334; Coverage: 99%)
Gene name: Cgl3062
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NA 2 x NA
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 87.039Å b: 127.586Å c: 87.155Å
α: 90° β: 92.96° γ: 90°
R-values:
R R work R free
0.223 0.223 0.258
Expression system: Escherichia coli

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