X-ray diffraction
2.4Å resolution

Complex of PI3K gamma with an inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Chain: A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2
Unit cell:
a: 144.302Å b: 68.244Å c: 106.069Å
α: 90° β: 95.19° γ: 90°
R R work R free
0.229 0.227 0.276
Expression system: Spodoptera frugiperda