3eb4

X-ray diffraction
2Å resolution

Voltage-dependent K+ channel beta subunit (I211R) in complex with cortisone

Released:
Source organism: Rattus norvegicus

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-gated potassium channel subunit beta-2 Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 36.62 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P62483 (Residues: 35-361; Coverage: 89%)
Gene names: Ckbeta2, Kcnab2, Kcnb3
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: I422
Unit cell:
a: 113.26Å b: 113.26Å c: 147.266Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.256
Expression system: Escherichia coli