Assemblies
Assembly Name:
Insulin complex
Multimeric state:
hetero dimer
Accessible surface area:
3463.88 Å2
Buried surface area:
1920.35 Å2
Dissociation area:
869.83
Å2
Dissociation energy (ΔGdiss):
12.67
kcal/mol
Dissociation entropy (TΔSdiss):
8.14
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134182
Assembly Name:
Insulin complex
Multimeric state:
hetero dimer
Accessible surface area:
3719.75 Å2
Buried surface area:
1827.38 Å2
Dissociation area:
839.84
Å2
Dissociation energy (ΔGdiss):
10.48
kcal/mol
Dissociation entropy (TΔSdiss):
8.17
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134182
Assembly Name:
Insulin A chain
Multimeric state:
hetero dodecamer
Accessible surface area:
11652.58 Å2
Buried surface area:
20762.12 Å2
Dissociation area:
4,629.94
Å2
Dissociation energy (ΔGdiss):
67.37
kcal/mol
Dissociation entropy (TΔSdiss):
12.86
kcal/mol
Symmetry number:
6
PDBe Complex ID:
PDB-CPX-134235
Assembly Name:
Insulin A chain
Multimeric state:
hetero dodecamer
Accessible surface area:
18517.79 Å2
Buried surface area:
13896.91 Å2
Dissociation area:
1,047.45
Å2
Dissociation energy (ΔGdiss):
1.5
kcal/mol
Dissociation entropy (TΔSdiss):
11.88
kcal/mol
Symmetry number:
6
PDBe Complex ID:
PDB-CPX-134235
Assembly Name:
Insulin A chain
Multimeric state:
hetero hexamer
Accessible surface area:
9968.72 Å2
Buried surface area:
5993.16 Å2
Dissociation area:
285.95
Å2
Dissociation energy (ΔGdiss):
15.23
kcal/mol
Dissociation entropy (TΔSdiss):
21.46
kcal/mol
Symmetry number:
3
PDBe Complex ID:
PDB-CPX-134224
Assembly Name:
Insulin A chain
Multimeric state:
hetero hexamer
Accessible surface area:
10633.16 Å2
Buried surface area:
5819.66 Å2
Dissociation area:
287.77
Å2
Dissociation energy (ΔGdiss):
20.12
kcal/mol
Dissociation entropy (TΔSdiss):
21.73
kcal/mol
Symmetry number:
3
PDBe Complex ID:
PDB-CPX-134224
Assembly Name:
Insulin A chain
Multimeric state:
hetero tetramer
Accessible surface area:
5514.92 Å2
Buried surface area:
5419.61 Å2
Dissociation area:
877.45
Å2
Dissociation energy (ΔGdiss):
5.16
kcal/mol
Dissociation entropy (TΔSdiss):
9.64
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-134210
Assembly Name:
Insulin A chain
Multimeric state:
hetero tetramer
Accessible surface area:
5848.94 Å2
Buried surface area:
5082.42 Å2
Dissociation area:
670.51
Å2
Dissociation energy (ΔGdiss):
2.35
kcal/mol
Dissociation entropy (TΔSdiss):
9.59
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-134210
Macromolecules
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
InterPro:
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01308 (Residues: 90-110; Coverage: 24%)
InterPro:
Chains: B, D
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Insulin/IGF/Relaxin family
InterPro:
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01308 (Residues: 25-53; Coverage: 34%)
Pfam: Insulin/IGF/Relaxin family
InterPro:
