Assemblies
Assembly Name:
Insulin complex
Multimeric state:
hetero dimer
Accessible surface area:
3490.32 Å2
Buried surface area:
1996.13 Å2
Dissociation area:
902.01
Å2
Dissociation energy (ΔGdiss):
12.7
kcal/mol
Dissociation entropy (TΔSdiss):
8.17
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134182
Assembly Name:
Insulin complex
Multimeric state:
hetero dimer
Accessible surface area:
3639.83 Å2
Buried surface area:
1875.14 Å2
Dissociation area:
839.67
Å2
Dissociation energy (ΔGdiss):
10.07
kcal/mol
Dissociation entropy (TΔSdiss):
8.16
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134182
Assembly Name:
Insulin A chain
Multimeric state:
hetero dodecamer
Accessible surface area:
11916.32 Å2
Buried surface area:
20187.81 Å2
Dissociation area:
195.77
Å2
Dissociation energy (ΔGdiss):
53.95
kcal/mol
Dissociation entropy (TΔSdiss):
2.22
kcal/mol
Symmetry number:
6
PDBe Complex ID:
PDB-CPX-134235
Assembly Name:
Insulin A chain
Multimeric state:
hetero dodecamer
Accessible surface area:
18383.31 Å2
Buried surface area:
13720.83 Å2
Dissociation area:
1,220.72
Å2
Dissociation energy (ΔGdiss):
2.67
kcal/mol
Dissociation entropy (TΔSdiss):
11.92
kcal/mol
Symmetry number:
6
PDBe Complex ID:
PDB-CPX-134235
Assembly Name:
Insulin A chain
Multimeric state:
hetero hexamer
Accessible surface area:
10171.47 Å2
Buried surface area:
5836.13 Å2
Dissociation area:
192.32
Å2
Dissociation energy (ΔGdiss):
7.59
kcal/mol
Dissociation entropy (TΔSdiss):
20.19
kcal/mol
Symmetry number:
3
PDBe Complex ID:
PDB-CPX-134224
Assembly Name:
Insulin A chain
Multimeric state:
hetero hexamer
Accessible surface area:
10640.37 Å2
Buried surface area:
5456.17 Å2
Dissociation area:
193.21
Å2
Dissociation energy (ΔGdiss):
7.89
kcal/mol
Dissociation entropy (TΔSdiss):
20.21
kcal/mol
Symmetry number:
3
PDBe Complex ID:
PDB-CPX-134224
Assembly Name:
Insulin A chain
Multimeric state:
hetero tetramer
Accessible surface area:
5487.72 Å2
Buried surface area:
5512.63 Å2
Dissociation area:
877.94
Å2
Dissociation energy (ΔGdiss):
5.56
kcal/mol
Dissociation entropy (TΔSdiss):
9.65
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-134210
Assembly Name:
Insulin A chain
Multimeric state:
hetero tetramer
Accessible surface area:
5790.67 Å2
Buried surface area:
5210.76 Å2
Dissociation area:
673.16
Å2
Dissociation energy (ΔGdiss):
2.28
kcal/mol
Dissociation entropy (TΔSdiss):
9.6
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-134210
Macromolecules
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
InterPro:
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01308 (Residues: 90-110; Coverage: 24%)
InterPro:
Chains: B, D
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Insulin/IGF/Relaxin family
InterPro:
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01308 (Residues: 25-53; Coverage: 34%)
Pfam: Insulin/IGF/Relaxin family
InterPro:
