3e6u

X-ray diffraction
2.6Å resolution

Crystal structure of Human LanCL1

Released:

Function and Biology Details

Reaction catalysed:
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase LANCL1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 411 amino acids
Theoretical weight: 46.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O43813 (Residues: 1-399; Coverage: 100%)
Gene names: GPR69A, LANCL1
Sequence domains: Lanthionine synthetase C-like protein
Structure domains: Glycosyltransferase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P3221
Unit cell:
a: 194.278Å b: 194.278Å c: 211.829Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.247 0.246 0.275
Expression system: Escherichia coli BL21