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X-ray structure of human prostasin in complex with Benzoxazole warhead peptidomimic, lysine in P3

X-ray diffraction
1.6Å resolution
PDB entry 3e16 coloured by chain, front view.
PDB entry 3e16 coloured by chain, side view.
PDB entry 3e16 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Prostasin heavy chain
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-172540

Macromolecules

Prostasin heavy chain
Chain: B
Length: 271 amino acids
Theoretical weight: 29.61 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q16651 (Residues: 45-305; Coverage: 83%)
Gene name: PRSS8
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
Prostasin heavy chain in PDB entry 3e16, assembly 1, front view.
Prostasin heavy chain in PDB entry 3e16, assembly 1, side view.
Prostasin heavy chain in PDB entry 3e16, assembly 1, top view.
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