› 3e15

X-ray diffraction
2Å resolution

6-phosphogluconolactonase from Plasmodium vivax

Released:
DOI: 10.2210/pdb3e15/pdb
PDB entry 3e15 coloured by chain, front view.
PDB entry 3e15 coloured by chain, side view.
PDB entry 3e15 coloured by chain, top view.
Source organism: Plasmodium vivax
Entry authors: Arakaki TL, Merritt EA

Function and Biology Details

Reaction catalysed: 
D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107662 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
glucose-6-phosphate dehydrogenase (NADP(+)) Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 312 amino acids
Theoretical weight: 36.67 KDa
Source organism: Plasmodium vivax
Expression system: Escherichia coli
UniProt:
  • Canonical: A5K3M1 (Residues: 2-304; Coverage: 33%)
Gene name: PVX_117790
Sequence domains: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
Structure domains: Rossmann fold

Ligands and Environments

3 bound ligands:
Ligand CL 2 x CL
Ligand K 4 x K
Ligand AZI 4 x AZI
1 modified residue:
Ligand MSE 32 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P1
Unit cell:
a: 46.524Å b: 80.846Å c: 89.765Å
α: 63.98° β: 88.1° γ: 80.01°
R-values:
R R work R free
0.152 0.15 0.202
Expression system: Escherichia coli

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