3dwq

X-ray diffraction
2.1Å resolution

Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Subtilase cytotoxin SubB Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 126 amino acids
Theoretical weight: 14.03 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3ZTX8 (Residues: 24-141; Coverage: 100%)
Gene names: C9098_24495, C9Z37_27580, C9Z78_25705, LH0182, subB
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P65
Unit cell:
a: 97.253Å b: 97.253Å c: 163.52Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.211 0.262
Expression system: Escherichia coli