› 3dwd

X-ray diffraction
2.4Å resolution

Crystal structure of the ArfGAP domain of human ARFGAP1

Released:
DOI: 10.2210/pdb3dwd/pdb
PDB entry 3dwd coloured by chain, front view.
PDB entry 3dwd coloured by chain, side view.
PDB entry 3dwd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nedyalkova L, Tong Y, Tempel W, Landry R, Arrowsmith CH, Edwards AM, Bountra C, Wilkstrom M, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor GTPase-activating protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 147 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N6T3 (Residues: 1-128; Coverage: 32%)
Gene names: ARF1GAP, ARFGAP1
Sequence domains: Putative GTPase activating protein for Arf
Structure domains: Arf GTPase activating protein

Ligands and Environments

2 bound ligands:
Ligand ZN 2 x ZN
Ligand UNX 2 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6
Unit cell:
a: 82.422Å b: 82.422Å c: 81.008Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.234 0.273
Expression system: Escherichia coli

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