› 3duz

X-ray diffraction
2.95Å resolution

Crystal structure of the postfusion form of baculovirus fusion protein GP64

Released:
DOI: 10.2210/pdb3duz/pdb
PDB entry 3duz coloured by chain, front view.
PDB entry 3duz coloured by chain, side view.
PDB entry 3duz coloured by chain, top view.
Source organism: Autographa californica nucleopolyhedrovirus
Primary publication:
The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines.
Kadlec J, Loureiro S, Abrescia NG, Stuart DI, Jones IM
Nat Struct Mol Biol 15 1024-30 (2008)
PMID: 18776902

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148076 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major envelope glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 487 amino acids
Theoretical weight: 55.87 KDa
Source organism: Autographa californica nucleopolyhedrovirus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P17501 (Residues: 21-499; Coverage: 97%)
Gene names: GP64, GP67, ORF128
Sequence domains: Baculovirus gp64 envelope glycoprotein family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand HG 5 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: R32
Unit cell:
a: 87.47Å b: 87.47Å c: 431.59Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.224 0.27
Expression system: Spodoptera frugiperda

Quick links

Citations

30 review citations

Fusing structure and function: a structural view of the herpesvirus entry machinery.
Connolly et al. (2011)
29 more

14 mentions without citation

Herpesvirus gB: A Finely Tuned Fusion Machine.
Cooper et al. (2015)
13 more