X-ray diffraction
4.19Å resolution

Crystal structure of Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, N-terminal eight Ig domains


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Down syndrome cell adhesion molecule 1, isoform O Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 816 amino acids
Theoretical weight: 89.73 KDa
Source organism: Drosophila melanogaster
Expression system: Trichoplusia ni
  • Canonical: Q0E9I4 (Residues: 1-810; Coverage: 39%)
Gene names: 43Bc, CG17800, CT39257, DSCAM, DScam, DmDscam, Dm_2R:13579, Dm_2R:13612, Dmel\CG17800, Dmel_CG17800, DsCam, Dscam, Dscam-hv, Dscam1, Dsm, Neu1, dScam, dscam, dscam1, l(2)05518, l(2)43Bc, p270
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: I222
Unit cell:
a: 118.46Å b: 177.61Å c: 434.05Å
α: 90° β: 90° γ: 90°
R R work R free
0.282 0.28 0.327
Expression system: Trichoplusia ni