3dkp

X-ray diffraction
2.1Å resolution

Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable ATP-dependent RNA helicase DDX52 Chain: A
Molecule details ›
Chain: A
Length: 245 amino acids
Theoretical weight: 27.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y2R4 (Residues: 139-381; Coverage: 41%)
Gene names: DDX52, HUSSY-19, ROK1
Sequence domains: DEAD/DEAH box helicase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 40.63Å b: 38.36Å c: 73.84Å
α: 90° β: 90.37° γ: 90°
R-values:
R R work R free
0.185 0.182 0.236
Expression system: Escherichia coli