3dfl

X-ray diffraction
2Å resolution

Crystal structure of human Prostasin complexed to 4-guanidinobenzoic acid

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prostasin heavy chain Chain: A
Molecule details ›
Chain: A
Length: 263 amino acids
Theoretical weight: 28.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16651 (Residues: 45-289; Coverage: 78%)
Gene name: PRSS8
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 53.498Å b: 54.846Å c: 83.279Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.173 0.225
Expression system: Escherichia coli