3d4m

X-ray diffraction
2.05Å resolution

Glutaredoxin 2 oxidized structure

Released:
Source organism: Saccharomyces cerevisiae
Entry authors: Discola KF, de Oliveira MA, Barcena JA, Porras P, Guimaraes BG, Netto LES

Function and Biology Details

Reactions catalysed:
RX + glutathione = HX + R-S-glutathione
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutaredoxin-2 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 11.98 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P17695 (Residues: 35-143; Coverage: 76%)
Gene names: D9719.17, GRX2, TTR, TTR1, YDR513W
Sequence domains: Glutaredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P41212
Unit cell:
a: 47.634Å b: 47.634Å c: 94.592Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.219
Expression system: Escherichia coli