Assemblies
Assembly Name:
Cellular tumor antigen p53 and DNA
Multimeric state:
hetero tetramer
Accessible surface area:
21117.74 Å2
Buried surface area:
3734.06 Å2
Dissociation area:
792.66
Å2
Dissociation energy (ΔGdiss):
3.51
kcal/mol
Dissociation entropy (TΔSdiss):
12.32
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-116165
Assembly Name:
Cellular tumor antigen p53 and DNA
Multimeric state:
hetero tetramer
Accessible surface area:
20985.85 Å2
Buried surface area:
4002.64 Å2
Dissociation area:
1,399.14
Å2
Dissociation energy (ΔGdiss):
2.49
kcal/mol
Dissociation entropy (TΔSdiss):
23.04
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-116165
Macromolecules
Chains: A, B, C, D
Length: 200 amino acids
Theoretical weight: 22.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: P53 DNA-binding domain
InterPro:
Length: 200 amino acids
Theoretical weight: 22.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P04637 (Residues: 94-293; Coverage: 51%)
Pfam: P53 DNA-binding domain
InterPro:
- p53 tumour suppressor family
- p53/RUNT-type transcription factor, DNA-binding domain superfamily
- p53-like transcription factor, DNA-binding domain superfamily
- p53, DNA-binding domain
Name:
DNA (5'-D(*DCP*DGP*DGP*DGP*DCP*DAP*DTP*DGP*DCP*DCP*DCP*DG)-3')
Representative chains: E, F, G, H
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Representative chains: E, F, G, H
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 12 nucleotides
Theoretical weight: 3.66 KDa