3cwz

X-ray diffraction
3.2Å resolution

Structure of RAB6(GTP)-R6IP1 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Rab-6A Chain: A
Molecule details ›
Chain: A
Length: 188 amino acids
Theoretical weight: 21.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20340 (Residues: 8-195; Coverage: 90%)
Gene names: RAB6, RAB6A
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
DENN domain-containing protein 5A Chain: B
Molecule details ›
Chain: B
Length: 384 amino acids
Theoretical weight: 44.01 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PAL8 (Residues: 707-1090; Coverage: 30%)
Gene names: Dennd5a, Rab6ip1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14, ESRF BEAMLINE ID14-1
Spacegroup: P6122
Unit cell:
a: 100.24Å b: 100.24Å c: 299.25Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.246 0.246 0.302
Expression system: Escherichia coli