3cjr

X-ray diffraction
2.05Å resolution

Ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11 (K39A) and inhibitor Sinefungin.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribosomal protein L11 methyltransferase Chain: A
Molecule details ›
Chain: A
Length: 254 amino acids
Theoretical weight: 27.66 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q84BQ9 (Residues: 1-254; Coverage: 100%)
Gene names: TTHA0656, prmA
Sequence domains: Ribosomal protein L11 methyltransferase (PrmA)
Structure domains:
50S ribosomal protein L11 Chain: B
Molecule details ›
Chain: B
Length: 147 amino acids
Theoretical weight: 15.47 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: P36238 (Residues: 1-147; Coverage: 100%)
Gene names: rpl11, rplK
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P65
Unit cell:
a: 132.742Å b: 132.742Å c: 46.056Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.213 0.277
Expression system: Escherichia coli