PDBe 3cjj

X-ray diffraction
1.85Å resolution

Crystal structure of human rage ligand-binding domain

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Advanced glycosylation end product-specific receptor Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 24.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15109 (Residues: 23-240; Coverage: 57%)
Gene names: AGER, RAGE
Sequence domains: CD80-like C2-set immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21212
Unit cell:
a: 74.85Å b: 119.96Å c: 28.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.209 0.24
Expression system: Escherichia coli