Assemblies
Assembly Name:
CD94-NKG2A natural killer receptor complex
Multimeric state:
hetero pentamer
Accessible surface area:
30351.68 Å2
Buried surface area:
8677.68 Å2
Dissociation area:
2,015.06
Å2
Dissociation energy (ΔGdiss):
-13.21
kcal/mol
Dissociation entropy (TΔSdiss):
24.45
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-146744
Assembly Name:
CD94-NKG2A natural killer receptor complex
Multimeric state:
hetero pentamer
Accessible surface area:
30595.77 Å2
Buried surface area:
8420.85 Å2
Dissociation area:
1,871.4
Å2
Dissociation energy (ΔGdiss):
-12.98
kcal/mol
Dissociation entropy (TΔSdiss):
24.42
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-146744
Macromolecules
Chains: A, D
Length: 273 amino acids
Theoretical weight: 31.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 273 amino acids
Theoretical weight: 31.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P13747 (Residues: 23-295; Coverage: 81%)
Pfam:
InterPro:
- MHC class I-like antigen recognition-like
- MHC classes I/II-like antigen recognition protein
- MHC class I-like antigen recognition-like superfamily
- MHC class I alpha chain, alpha1 alpha2 domains
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
Chains: B, E
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Immunoglobulin C1-set domain
InterPro:
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Pfam: Immunoglobulin C1-set domain
InterPro:
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
- Beta-2-Microglobulin
Chains: C, F
Length: 9 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 9 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P17693 (Residues: 3-11; Coverage: 0%)
Chains: G, I
Length: 121 amino acids
Theoretical weight: 14.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Lectin C-type domain
InterPro:
Length: 121 amino acids
Theoretical weight: 14.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13241 (Residues: 59-179; Coverage: 68%)
Pfam: Lectin C-type domain
InterPro:
- EGF-like domain
- C-type lectin-like/link domain superfamily
- C-type lectin fold
- C-type lectin-like
- Natural killer cell receptor-like, C-type lectin-like domain
Chains: H, J
Length: 120 amino acids
Theoretical weight: 13.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Lectin C-type domain
InterPro:
Length: 120 amino acids
Theoretical weight: 13.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P26715 (Residues: 113-232; Coverage: 52%)
Pfam: Lectin C-type domain
InterPro: