3c98

X-ray diffraction
2.6Å resolution

Revised structure of the munc18a-syntaxin1 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Syntaxin-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 606 amino acids
Theoretical weight: 69.07 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P61765 (Residues: 1-594; Coverage: 100%)
Gene names: Stxbp1, Unc18a
Sequence domains: Sec1 family
Structure domains:
Syntaxin-1A Chain: B
Molecule details ›
Chain: B
Length: 279 amino acids
Theoretical weight: 32.45 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P32851 (Residues: 1-267; Coverage: 93%)
Gene names: Sap, Stx1a
Sequence domains: Syntaxin
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P4212
Unit cell:
a: 158.07Å b: 158.07Å c: 81.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.203 0.263
Expression system: Escherichia coli