› › Structure analysis

Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20

X-ray diffraction
3.4Å resolution
PDB entry 3c6l coloured by chain, front view.
PDB entry 3c6l coloured by chain, side view.
PDB entry 3c6l coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero octamer (preferred)
Entry contents: 4 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero octamer
Accessible surface area: 70801.71 Å2
Buried surface area: 27039.4 Å2
Dissociation area: 3,700.93 Å2
Dissociation energy (ΔGdiss): -19.03 kcal/mol
Dissociation entropy (TΔSdiss): 43.59 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-210601

Macromolecules

TCR 2W20 alpha chain
Chains: A, E
Length: 185 amino acids
Theoretical weight: 20.96 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
InterPro:
CATH: Immunoglobulins
SCOP:
TCR 2W20 alpha chain in PDB entry 3c6l, assembly 1, front view.
TCR 2W20 alpha chain in PDB entry 3c6l, assembly 1, side view.
TCR 2W20 alpha chain in PDB entry 3c6l, assembly 1, top view.
Molecule details ›

Search similar proteins

TCR 2W20 beta chain
Chains: B, F
Length: 236 amino acids
Theoretical weight: 26.49 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
InterPro:
CATH: Immunoglobulins
TCR 2W20 beta chain in PDB entry 3c6l, assembly 1, front view.
TCR 2W20 beta chain in PDB entry 3c6l, assembly 1, side view.
TCR 2W20 beta chain in PDB entry 3c6l, assembly 1, top view.
Molecule details ›

Search similar proteins

H-2 class II histocompatibility antigen, A-B alpha chain
Chains: C, G
Length: 182 amino acids
Theoretical weight: 20.6 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P14434 (Residues: 27-208; Coverage: 78%)
Gene name: H2-Aa
Pfam:
InterPro:
CATH:
SCOP:
H-2 class II histocompatibility antigen, A-B alpha chain in PDB entry 3c6l, assembly 1, front view.
H-2 class II histocompatibility antigen, A-B alpha chain in PDB entry 3c6l, assembly 1, side view.
H-2 class II histocompatibility antigen, A-B alpha chain in PDB entry 3c6l, assembly 1, top view.
Molecule details ›

Search similar proteins

H-2 class II histocompatibility antigen, A beta chain
Chains: D, H
Length: 217 amino acids
Theoretical weight: 24.94 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P14483 (Residues: 21-218; Coverage: 77%)
Gene names: H2-Ab1, H2-iabeta
Pfam:
InterPro:
CATH:
SCOP:
H-2 class II histocompatibility antigen, A beta chain in PDB entry 3c6l, assembly 1, front view.
H-2 class II histocompatibility antigen, A beta chain in PDB entry 3c6l, assembly 1, side view.
H-2 class II histocompatibility antigen, A beta chain in PDB entry 3c6l, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links