3c33

X-ray diffraction
1.72Å resolution

Crystal structure of GluR5 ligand-binding core in complex with potassium at 1.78 Angstrom resolution

Released:
Source organism: Rattus norvegicus
Primary publication:
Molecular basis of kainate receptor modulation by sodium.
Neuron 58 720-35 (2008)
PMID: 18549784

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, kainate 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 258 amino acids
Theoretical weight: 29.25 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P22756 (Residues: 446-559, 682-821; Coverage: 28%)
Gene names: Glur5, Grik1
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P41212
Unit cell:
a: 70.742Å b: 70.742Å c: 234.46Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.165 0.194
Expression system: Escherichia coli