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Crystal structure of TetR transcriptional regulator from Agrobacterium tumefaciens

Source organism: Agrobacterium fabrum str. C58
Biochemical function: DNA-binding transcription factor activity
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF14246
Domain description: AefR-like transcriptional repressor, C-terminal domain
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3c2b contains 2 copies of Pfam domain PF14246 (AefR-like transcriptional repressor, C-terminal domain) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

PF00440
Domain description: Bacterial regulatory proteins, tetR family
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3c2b contains 2 copies of Pfam domain PF00440 (Bacterial regulatory proteins, tetR family) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001647
Domain description: DNA-binding HTH domain, TetR-type
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR039536
Domain description: Transcriptional regulator TetR, C-terminal, Proteobacteria type
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR036271
Domain description: Tetracyclin repressor-like, C-terminal domain superfamily
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR009057
Domain description: Homeobox-like domain superfamily
Occurring in:
  1. HTH tetR-type domain-containing protein

Structure domains

CATH CATH domains
1.10.357.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Tetracycline Repressor; domain 2
Homology: Tetracycline Repressor, domain 2
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3c2b contains 2 copies of CATH domain 1.10.357.10 (Tetracycline Repressor; domain 2) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.
1.10.10.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeodomain-like
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3c2b contains 2 copies of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

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