X-ray diffraction
2.85Å resolution

crystal structure of QacR(E58Q) bound to berberine


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexadecamer
Entry contents:
1 distinct polypeptide molecule
HTH-type transcriptional regulator QacR Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 188 amino acids
Theoretical weight: 22.15 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P0A0N3 (Residues: 1-188; Coverage: 100%)
Gene names: SAVP031, qacR
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P42212
Unit cell:
a: 171.48Å b: 171.48Å c: 94.4Å
α: 90° β: 90° γ: 90°
R R work R free
0.217 0.217 0.275
Expression system: Escherichia coli BL21(DE3)