3bj4

X-ray diffraction
2Å resolution

The KCNQ1 (Kv7.1) C-terminus, a multi-tiered scaffold for subunit assembly and protein interaction

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel subfamily KQT member 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 49 amino acids
Theoretical weight: 5.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P51787 (Residues: 574-622; Coverage: 7%)
Gene names: KCNA8, KCNA9, KCNQ1, KVLQT1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P3121
Unit cell:
a: 51.321Å b: 51.321Å c: 71.094Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.223 0.221 0.255
Expression system: Escherichia coli