3bdx

X-ray diffraction
2.3Å resolution

Crystal structure of the unstable and highly fibrillogenic Pro7Ser mutant of the Recombinant variable domain 6AJL2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo trimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid lambda 6 light chain variable region PIP (fragment) Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 111 amino acids
Theoretical weight: 11.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 56.11Å b: 106.12Å c: 133.36Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.205 0.246
Expression system: Escherichia coli