› 3bdq

X-ray diffraction
2Å resolution

Room Tempreture Crystal Structure of Sterol Carrier Protein-2 Like-2

Released:
DOI: 10.2210/pdb3bdq/pdb
PDB entry 3bdq coloured by chain, front view.
PDB entry 3bdq coloured by chain, side view.
PDB entry 3bdq coloured by chain, top view.
Source organism: Aedes aegypti
Primary publication:
Three-dimensional structure/function analysis of SCP-2-like2 reveals differences among SCP-2 family members.
Dyer DH, Wessely V, Forest KT, Lan Q
J Lipid Res 49 644-53 (2008)
PMID: 18084051

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170940 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SCP2 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 110 amino acids
Theoretical weight: 11.62 KDa
Source organism: Aedes aegypti
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q0GY13 (Residues: 1-105; Coverage: 100%)
Sequence domains: SCP-2 sterol transfer family
Structure domains: SCP2 sterol-binding domain

Ligands and Environments

1 bound ligand:
Ligand PLM 3 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P21
Unit cell:
a: 46.25Å b: 57.25Å c: 49.1Å
α: 90° β: 114.96° γ: 90°
R-values:
R R work R free
0.188 0.186 0.23
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

A novel model of cholesterol efflux from lipid-loaded cells.
Luo et al. (2010)
1 more

2 mentions without citation

Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.
Park et al. (2010)
1 more