3bcg

X-ray diffraction
2.48Å resolution

Conformational changes of the AcrR regulator reveal a mechanism of induction

Released:
Source organism: Escherichia coli K-12
Primary publication:
Conformational change of the AcrR regulator reveals a possible mechanism of induction.
Acta Crystallogr Sect F Struct Biol Cryst Commun 64 584-8 (2008)
PMID: 18607081

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator AcrR Chains: A, B
Molecule details ›
Chains: A, B
Length: 215 amino acids
Theoretical weight: 24.8 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P0ACS9 (Residues: 1-215; Coverage: 100%)
Gene names: JW0453, acrR, b0464, ybaH
Sequence domains: MAATS-type transcriptional repressor, C-terminal region
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P31
Unit cell:
a: 46.66Å b: 46.66Å c: 166.155Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.214 0.268
Expression system: Escherichia coli K-12