3bbc

X-ray diffraction
1.7Å resolution

Crystal structure of R88A mutant of the NM23-H2 transcription factor

Released:

Function and Biology Details

Reactions catalysed:
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside diphosphate kinase B Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 151 amino acids
Theoretical weight: 17.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P22392 (Residues: 2-152; Coverage: 99%)
Gene names: NM23B, NME2
Sequence domains: Nucleoside diphosphate kinase
Structure domains: Nucleoside diphosphate kinase-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P212121
Unit cell:
a: 71.756Å b: 104.616Å c: 118.089Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.174 0.216
Expression system: Escherichia coli