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EuHMT1 (Glp) Ankyrin Repeat Domain (Structure 1)

Source organism: Homo sapiens
Biochemical function: histone methyltransferase activity
Biological process: not assigned
Cellular component: not assigned

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EC 2.1.1.367: [Histone H3]-lysine(9) N-methyltransferase

Reaction catalysed:
S-adenosyl-L-methionine + a [histone H3]-L-lysine(9) = S-adenosyl-L-homocysteine + a [histone H3]-N(6)-methyl-L-lysine(9)
Systematic name:
S-adenosyl-L-methionine:[histone H3]-L-lysine(9) N(6)-methyltransferase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF12796
Domain description: Ankyrin repeats (3 copies)
Occurring in:
  1. Histone-lysine N-methyltransferase EHMT1
The deposited structure of PDB entry 3b7b contains 6 copies of Pfam domain PF12796 (Ankyrin repeats (3 copies)) in Histone-lysine N-methyltransferase EHMT1. Showing 3 copies in chain A.

InterPro InterPro annotations
IPR002110
Domain description: Ankyrin repeat
Occurring in:
  1. Histone-lysine N-methyltransferase EHMT1
IPR036770
Domain description: Ankyrin repeat-containing domain superfamily
Occurring in:
  1. Histone-lysine N-methyltransferase EHMT1
IPR043550
Domain description: Histone-lysine N-methyltransferase EHMT1/EHMT2
Occurring in:
  1. Histone-lysine N-methyltransferase EHMT1

Structure domain

CATH CATH domain
1.25.40.20
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Ankyrin repeat-containing domain
Occurring in:
  1. Histone-lysine N-methyltransferase EHMT1
The deposited structure of PDB entry 3b7b contains 2 copies of CATH domain 1.25.40.20 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Histone-lysine N-methyltransferase EHMT1. Showing 1 copy in chain A.
SCOP SCOP annotation
83019
Class: Designed proteins
Fold: Artificial ankyrin repeat proteins
Superfamily: Artificial ankyrin repeat proteins
Occurring in:
  1. Histone-lysine N-methyltransferase EHMT1
The deposited structure of PDB entry 3b7b contains 1 copy of SCOP domain 83019 (Artificial ankyrin repeat proteins) in Histone-lysine N-methyltransferase EHMT1. Showing 1 copy in chain A.

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