› 3b4m

X-ray diffraction
2.82Å resolution

Crystal Structure of Human PABPN1 RRM

Released:
DOI: 10.2210/pdb3b4m/pdb
PDB entry 3b4m coloured by chain, front view.
PDB entry 3b4m coloured by chain, side view.
PDB entry 3b4m coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure and possible dimerization of the single RRM of human PABPN1.
Ge H, Zhou D, Tong S, Gao Y, Teng M, Niu L
Proteins 71 1539-45 (2008)
PMID: 18275081

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183174 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polyadenylate-binding protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 96 amino acids
Theoretical weight: 10.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q86U42 (Residues: 167-254; Coverage: 29%)
Gene names: PAB2, PABP2, PABPN1
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P31
Unit cell:
a: 59.338Å b: 59.338Å c: 80.599Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.226 0.29
Expression system: Escherichia coli BL21

Quick links

Citations

4 review citations

PABPN1: molecular function and muscle disease.
Banerjee et al. (2013)
3 more

3 mentions without citation

Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery.
Xiang et al. (2014)
2 more