EC 2.7.7.101: DNA primase DnaG
Reaction catalysed:
SsDNA + n NTP = ssDNA/pppN(pN)(n-1) hybrid + (n-1) diphosphate
Systematic name:
Nucleotide 5'-triphosphate:single-stranded DNA nucleotidyltransferase (DNA-RNA hybrid synthesizing)
Alternative Name(s):
- DnaG
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)![The deposited structure of PDB entry 3b39 contains 2 copies of Pfam domain PF10410 (DnaB-helicase binding domain of primase) in DNA primase. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3b39_2_A_Pfam_PF10410_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3b39</span> contains 2 copies of Pfam domain <span class='highlight'>PF10410 (DnaB-helicase binding domain of primase)</span> in <span class='highlight'>DNA primase</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
![The deposited structure of PDB entry 3b39 contains 2 copies of Pfam domain PF13155 (Toprim-like) in DNA primase. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3b39_2_A_Pfam_PF13155_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3b39</span> contains 2 copies of Pfam domain <span class='highlight'>PF13155 (Toprim-like)</span> in <span class='highlight'>DNA primase</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
![The deposited structure of PDB entry 3b39 contains 2 copies of Pfam domain PF08275 (DNA primase catalytic core, N-terminal domain) in DNA primase. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3b39_2_A_Pfam_PF08275_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3b39</span> contains 2 copies of Pfam domain <span class='highlight'>PF08275 (DNA primase catalytic core, N-terminal domain)</span> in <span class='highlight'>DNA primase</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
InterPro annotationsStructure domains
CATH domains
1.20.50.20
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
Pheromone ER-1
Homology:
DnaG, RNA polymerase domain, helical bundle
Occurring in:
![The deposited structure of PDB entry 3b39 contains 2 copies of CATH domain 1.20.50.20 (Pheromone ER-1) in DNA primase. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3b39_2_A_CATH_1.20.50.20_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3b39</span> contains 2 copies of CATH domain <span class='highlight'>1.20.50.20 (Pheromone ER-1)</span> in <span class='highlight'>DNA primase</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
3.40.1360.10
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Dna Topoisomerase Vi A Subunit; Chain: A, domain 2
Homology:
Dna Topoisomerase Vi A Subunit; Chain: A, domain 2
Occurring in:
![The deposited structure of PDB entry 3b39 contains 2 copies of CATH domain 3.40.1360.10 (Dna Topoisomerase Vi A Subunit; Chain: A, domain 2) in DNA primase. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3b39_2_A_CATH_3.40.1360.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3b39</span> contains 2 copies of CATH domain <span class='highlight'>3.40.1360.10 (Dna Topoisomerase Vi A Subunit; Chain: A, domain 2)</span> in <span class='highlight'>DNA primase</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
![The deposited structure of PDB entry 3b39 contains 2 copies of CATH domain 3.90.980.10 (DNA primase DNAg catalytic core, N-terminal domain) in DNA primase. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3b39_2_A_CATH_3.90.980.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3b39</span> contains 2 copies of CATH domain <span class='highlight'>3.90.980.10 (DNA primase DNAg catalytic core, N-terminal domain)</span> in <span class='highlight'>DNA primase</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")