X-ray diffraction
3.49Å resolution

Crystal Structure of the Kir3.2 Cytoplasmic Domain (Na+-free crystal soaked in 10 mM barium chloride and 10 mM Spermine)


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
G protein-activated inward rectifier potassium channel 2 Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.75 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P48542 (Residues: 199-381; Coverage: 43%)
  • Best match: P48542-3 (Residues: 199-318)
Gene names: Girk2, Kcnj6, Kcnj7, W
Sequence domains: Inward rectifier potassium channel C-terminal domain
Structure domains: G protein-activated inward rectifier potassium channel 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: I422
Unit cell:
a: 81.691Å b: 81.691Å c: 172.429Å
α: 90° β: 90° γ: 90°
R R work R free
0.23 0.221 0.28
Expression system: Escherichia coli