› 3asv

X-ray diffraction
2.7Å resolution

The Closed form of serine dehydrogenase complexed with NADP+

Released:
DOI: 10.2210/pdb3asv/pdb
PDB entry 3asv coloured by chain, front view.
PDB entry 3asv coloured by chain, side view.
PDB entry 3asv coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of serine dehydrogenase from Escherichia coli: important role of the C-terminal region for closed-complex formation.
Yamazawa R, Nakajima Y, Mushiake K, Yoshimoto T, Ito K
J Biochem 149 701-12 (2011)
PMID: 21349860

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163417 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Short-chain dehydrogenase/reductase SDR Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 248 amino acids
Theoretical weight: 27.28 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

2 bound ligands:
Ligand NAP 6 x NAP
Ligand PO4 6 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P64
Unit cell:
a: 113.859Å b: 113.859Å c: 197.54Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.192 0.192 0.273
Expression system: Escherichia coli

Quick links

Citations

10 citation in other articles

Biochemical studies and ligand-bound structures of biphenyl dehydrogenase from Pandoraea pnomenusa strain B-356 reveal a basis for broad specificity of the enzyme.
Dhindwal et al. (2011)
9 more

4 mentions without citation

Structure-based conversion of the coenzyme requirement of a short-chain dehydrogenase/reductase involved in bacterial alginate metabolism.
Takase et al. (2014)
3 more