› 3apb

X-ray diffraction
1.95Å resolution

Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with iodide

Released:
DOI: 10.2210/pdb3apb/pdb
PDB entry 3apb coloured by chain, front view.
PDB entry 3apb coloured by chain, side view.
PDB entry 3apb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Matsuzaka T, Ideo H, Yamashita K, Nonaka T

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 154 amino acids
Theoretical weight: 17.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00214 (Residues: 1-154; Coverage: 49%)
Gene name: LGALS8
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand IOD 29 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P212121
Unit cell:
a: 65.591Å b: 75.869Å c: 77.901Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.202 0.242
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Multifarious roles of sialic acids in immunity.
Varki et al. (2012)
21 more

1 mention without citation

Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans.
Ideo et al. (2011)