3a8n

X-ray diffraction
4.5Å resolution

Crystal structure of the Tiam1 PHCCEx domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor TIAM1 Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 31.62 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q60610 (Residues: 429-702; Coverage: 17%)
Gene names: Tiam-1, Tiam1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P6422
Unit cell:
a: 113.47Å b: 113.47Å c: 113.837Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.306 0.306 0.396
Expression system: Escherichia coli