Function and Biology Details
Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Signal transduction histidine kinase-related protein, C-terminal
- PAS domain
- Signal transduction response regulator, receiver domain
- Signal transduction histidine kinase, dimerisation/phosphoacceptor domain
- Histidine kinase/HSP90-like ATPase
- Histidine kinase/HSP90-like ATPase superfamily
- Transcriptional regulatory protein WalR-like
- CheY-like superfamily
4 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194769 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
histidine kinase
Molecule details ›
Chain: A
Length: 349 amino acids
Theoretical weight: 41 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 349 amino acids
Theoretical weight: 41 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9X180 (Residues: 408-755; Coverage: 46%)
Sequence domains:
- PAS fold
- His Kinase A (phospho-acceptor) domain
- Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Response regulatory domain-containing protein
Molecule details ›
Chain: B
Length: 116 amino acids
Theoretical weight: 13.52 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold
Length: 116 amino acids
Theoretical weight: 13.52 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9X181 (Residues: 1-116; Coverage: 100%)
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold
