3zys

Electron Microscopy
12.2Å resolution

Human dynamin 1 deltaPRD polymer stabilized with GMPPCP

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero 72-mer (preferred)
hetero hexamer
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Dynamin-1 Chains: A, D
Molecule details ›
Chains: A, D
Length: 353 amino acids
Theoretical weight: 39.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q05193 (Residues: 5-320, 726-750; Coverage: 40%)
Gene names: DNM, DNM1
Sequence domains: Dynamin family
Interferon-induced GTP-binding protein Mx1 Chains: B, E
Molecule details ›
Chains: B, E
Length: 662 amino acids
Theoretical weight: 75.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20591 (Residues: 1-662; Coverage: 100%)
Gene name: MX1
Sequence domains:
Dynamin-1 Chains: C, F
Molecule details ›
Chains: C, F
Length: 113 amino acids
Theoretical weight: 13.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05193 (Residues: 518-630; Coverage: 13%)
Gene names: DNM, DNM1
Sequence domains: PH domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 12.2Å
Relevant EMDB volumes: EMD-1949
Expression systems:
  • Escherichia coli BL21(DE3)
  • Escherichia coli