3zwz

X-ray diffraction
2.1Å resolution

Crystal structure of Plasmodium falciparum AMA1 in complex with a 39aa PfRON2 peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apical membrane antigen 1 Chain: A
Molecule details ›
Chain: A
Length: 347 amino acids
Theoretical weight: 39.44 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q7KQK5 (Residues: 103-438; Coverage: 54%)
Gene name: PF3D7_1133400
Structure domains: Hepatocyte Growth Factor
Rhoptry neck protein 2 Chain: B
Molecule details ›
Chain: B
Length: 39 amino acids
Theoretical weight: 4.07 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Not provided
UniProt:
  • Canonical: Q8IKV6 (Residues: 2021-2059; Coverage: 2%)
Gene name: PF3D7_1452000

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21
Unit cell:
a: 70.15Å b: 38.26Å c: 70.75Å
α: 90° β: 99.73° γ: 90°
R-values:
R R work R free
0.166 0.164 0.201
Expression systems:
  • Trichoplusia ni
  • Not provided