PDBe 3ztn

X-ray diffraction
3Å resolution

STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 36.39 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
UniProt:
  • Canonical: C3W5S1 (Residues: 18-344; Coverage: 58%)
Gene name: HA
Structure domains:
Hemagglutinin Chain: B
Molecule details ›
Chain: B
Length: 176 amino acids
Theoretical weight: 20.13 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
UniProt:
  • Canonical: C3W5S1 (Residues: 345-520; Coverage: 31%)
Gene name: HA
Structure domains: Hemagglutinin Ectodomain; Chain B
FI6V3 ANTIBODY LIGHT CHAIN Chain: H
Molecule details ›
Chain: H
Length: 226 amino acids
Theoretical weight: 24.56 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Structure domains: Immunoglobulins
FI6V3 ANTIBODY LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 218 amino acids
Theoretical weight: 24.11 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P4132
Unit cell:
a: 206.1Å b: 206.1Å c: 206.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.214 0.289
Expression system: Spodoptera frugiperda