3wxa

X-ray diffraction
2.36Å resolution

X-ray crystal structural analysis of the complex between ALG-2 and Sec31A peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Programmed cell death protein 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 172 amino acids
Theoretical weight: 20.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75340 (Residues: 20-191; Coverage: 90%)
Gene names: ALG2, PDCD6
Sequence domains:
Structure domains: EF-hand
Protein transport protein Sec31A Chains: C, D
Molecule details ›
Chains: C, D
Length: 12 amino acids
Theoretical weight: 1.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O94979 (Residues: 837-848; Coverage: 1%)
Gene names: HSPC275, HSPC334, KIAA0905, SEC31A, SEC31L1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P64
Unit cell:
a: 81.973Å b: 81.973Å c: 103.232Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.225 0.263
Expression systems:
  • Escherichia coli
  • Not provided