X-ray diffraction
1.95Å resolution

Crystal Structure of Nav1.6 IQ motif in complex with apo-CaM


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Calmodulin-1; Sodium channel protein type 8 subunit alpha Chains: B, C, D, E
Molecule details ›
Chains: B, C, D, E
Length: 182 amino acids
Theoretical weight: 20.48 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P0DP26 (Residues: 1-149; Coverage: 100%)
  • Canonical: Q9WTU3 (Residues: 1893-1914; Coverage: 1%)
Gene names: Calm, Calm1, Cam, Cam1, Nbna1, Scn8a
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P21
Unit cell:
a: 72.83Å b: 50.752Å c: 150.666Å
α: 90° β: 91.48° γ: 90°
R R work R free
0.201 0.2 0.237
Expression system: Escherichia coli