› 3w7z

X-ray diffraction
1.15Å resolution

1.15A structure of human 2Zn insulin at 293K

Released:
DOI: 10.2210/pdb3w7z/pdb
PDB 3w7z coloured by chain and viewed from the front.
PDB 3w7z coloured by chain and viewed from the side.
PDB 3w7z coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Hoshikawa N, Sasaki K, Sakabe N, Sakabe K

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
Non-polymer only hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Gene name: INS

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6C
Spacegroup: R3
Unit cell:
a: 82.7Å b: 82.7Å c: 34.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.148 0.145 0.195

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