3w4u

X-ray diffraction
1.95Å resolution

Human zeta-2 beta-2-s hemoglobin

Released:
Source organism: Homo sapiens
Primary publication:
Structure of fully liganded Hb ζ2β2(s) trapped in a tense conformation.
Acta Crystallogr. D Biol. Crystallogr. 69 2061-71 (2013)
PMID: 24100324

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit zeta Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 142 amino acids
Theoretical weight: 15.66 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: P02008 (Residues: 1-142; Coverage: 100%)
Gene names: HBZ, HBZ2
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 146 amino acids
Theoretical weight: 15.86 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P3121
Unit cell:
a: 115.54Å b: 115.54Å c: 140.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.205 0.255
Expression system: Mus musculus