3w34

X-ray diffraction
1.91Å resolution

Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates

Released:

Function and Biology Details

Reaction catalysed:
ATP + cytidine = ADP + CMP
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uridine kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 211 amino acids
Theoretical weight: 23.71 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SKR5 (Residues: 1-211; Coverage: 100%)
Gene names: TTHA0578, udk
Sequence domains: Phosphoribulokinase / Uridine kinase family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21212
Unit cell:
a: 68.73Å b: 126.952Å c: 61.726Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 0.243
Expression system: Escherichia coli