X-ray diffraction
2.4Å resolution

Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae

Source organism: Neisseria gonorrhoeae
Entry authors: Kumaraswami M, Shafer WM, Brennan RG

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
HTH-type transcriptional regulator MtrR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 210 amino acids
Theoretical weight: 24.29 KDa
Source organism: Neisseria gonorrhoeae
Expression system: Escherichia coli
  • Canonical: P39897 (Residues: 1-210; Coverage: 100%)
Gene name: mtrR
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2
Unit cell:
a: 218.3Å b: 84.6Å c: 58.1Å
α: 90° β: 103.9° γ: 90°
R R work R free
0.212 0.212 0.256
Expression system: Escherichia coli